有几种技术被部署在治疗一些疾病,如肺癌和HNC使用基因疗法。体内有几个流程的部署,以实现一个成功的基因疗法。有几项研究已经展示了使用基因转移以及肿瘤控制机制的CD / 1型单纯疱疹病毒TK-containing腺病毒与5-FC相关联或GCV疗法(索尼,2004)。有几次提高基因的表达及其交付使用一些含有CD / 1型单纯疱疹病毒TK基因的腺病毒。Ad5-CD / TKrep存在细胞治疗和细胞溶解的。Ad5-CD / TKrep高度有效地破坏肿瘤细胞(https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2871252/)。
There had been several techniques which had been deployed in order to treat several diseases like lung cancer and HNC using the gene therapy. There are several in-vivo processes which are deployed in order to achieve a successful gene therapy. There had been several studies which have showcased the use of gene transfer as well as tumour control mechanism of the CD/ HSV-1 TK-containing adenoviruses which are associated with 5-FC or the GCV therapy (Sonis, 2004). There had been several attempts to improve the expression of a gene and its delivery using several adenoviruses that contain the CD/ HSV-1 TK gene. Ad5-CD/TKrep that is present the cells are therapeutic and cytolytic in nature. Ad5-CD/TKrep is highly effective in destroying the tumour cells (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2871252/).
Gene therapy also finds its implication as a virotherapy which is also used for the treatment of cancer. There are several viruses which can carry genes in them and are of therapeutic use to the host body. There are conditionally replicative adenoviruses (CRAds) which actively replicate in the body of the host and help in improving the viral effect in the host (https://theoncologist.alphamedpress.org/content/7/suppl_4/2.full). Adenovirus with its presence in the blood helps in effectively moving out and countering several viral diseases (Niidome, 2002).