In the genre of smart field of drug delivery polymer generally play an important role, because it has the ability to deliver therapeutic agents directly into the site of action with best efficiency. The delivery system of smart drug has been made successfully by the use of advanced polymer science in the field of bionanotechnology. These advances have been recently applied in different medical applications for structures of nano scale in the delivery system of drug delivery. The delivery system of the smart drug should possess some other features that are very important like pre scheduled rate, self controlled, targeted and monitoring of delivery (Maeda, Nakamura & Fang, 2013). There are several biological applications that are used for nano scale as well as micro scale sized particles.
There are many polymeric nanoparticle systems that are used in the therapeutic treatment for cancer. According to Kim, Lee & Sidransky (2010), the properties of the nanoparticle systems systems need to be altered according to the property of the tumor. The hydrophilic system gives the nanoparticles properties of health that no longer circulate in the system. The types of nanoparticle systems are explored for application cancer therapy and it includes the dendrimers, polymers as well as the polymeric and nanoparticles. The large number of scope for modifying the chemical polymeric systems gives a facility to use it wisely for the targeted and therapeutic aspects (Hainfeld et al. 2010). The agent of therapeutic is the platforms of polymers and it includes the solid polymeric nanoparticles and polymeric micelle. The function of the nanoparticles assist for achieving the extended residence time of blood, and it also reduces the nonspecific distribution as well. The issue for target of the particular cells antigens a targeting ligand like peptide.
The negatively charged nanoparticles are more effective than the positively charged ones and the size of these particles range from 1-100 nm that help to increase the phagocytic capability of the cell and thereby enhancing the drug delivery system (Boman, 2010).